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Original Research 


A Randomized Controlled Trial of Palasadi Basti and Pathadi Choorna versus Metformin Hydrochloride in the Management of Polycystic Ovarian Syndrome (Artavadushti).

Archana S, Laxmipriya Dei.


Abstract
Introduction: Polycystic ovarian Syndrome is a common endocrine disorder that affects 4-18% of reproductive–aged women and 9 -30% of adolescent girls. We aimed to evaluate and compare the effect of Palasadi Basti & oral administration of Pathadi Choorna with that of Metformin Hydrochloride in the management of PCOS. Methodology: This single-centre, open-label, randomized controlled trial was conducted between April 2017 and November 2018. A total of 96 women diagnosed with PCOS based on the Rotterdam criteria and meeting the inclusion criteria were randomly assigned in a 1:1 ratio to receive either an Ayurvedic treatment protocol or standard medication for 3 months. The outcome parameters included intergroup variations in menstrual cycle interval, the duration and quantity of menstrual bleeding, BMI changes, reductions in the waist-to-hip ratio and the rate of conception among infertile individuals. Statistical analysis was performed using the t-test, the Wilcoxon signed-rank test & Mann–Whitney U test. Results: Ayurvedic treatment group showed significantly greater improvement in weight reduction & menstrual symptoms compared to Metformin group. Higher conception rates were noted among infertile women in the Ayurvedic group. Conclusion: Palashadi Basti and Pathadi Choorna were found to be more effective than Metformin Hydrochloride in improving the signs and symptoms of PCOS.

Key words: Menstrual irregularity, Infertility; Anovulation; Ayurveda, Palashadi basti, Yoga, BMI


 
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Pubmed Style

S A, Dei L. A Randomized Controlled Trial of Palasadi Basti and Pathadi Choorna versus Metformin Hydrochloride in the Management of Polycystic Ovarian Syndrome (Artavadushti).. AAM. 2025; 14(Supplement 1): 370-383. doi:10.5455/AAM.59828


Web Style

S A, Dei L. A Randomized Controlled Trial of Palasadi Basti and Pathadi Choorna versus Metformin Hydrochloride in the Management of Polycystic Ovarian Syndrome (Artavadushti).. https://www.aamjournal.in/?mno=59828 [Access: October 05, 2025]. doi:10.5455/AAM.59828


AMA (American Medical Association) Style

S A, Dei L. A Randomized Controlled Trial of Palasadi Basti and Pathadi Choorna versus Metformin Hydrochloride in the Management of Polycystic Ovarian Syndrome (Artavadushti).. AAM. 2025; 14(Supplement 1): 370-383. doi:10.5455/AAM.59828



Vancouver/ICMJE Style

S A, Dei L. A Randomized Controlled Trial of Palasadi Basti and Pathadi Choorna versus Metformin Hydrochloride in the Management of Polycystic Ovarian Syndrome (Artavadushti).. AAM. (2025), [cited October 05, 2025]; 14(Supplement 1): 370-383. doi:10.5455/AAM.59828



Harvard Style

S, A. & Dei, . L. (2025) A Randomized Controlled Trial of Palasadi Basti and Pathadi Choorna versus Metformin Hydrochloride in the Management of Polycystic Ovarian Syndrome (Artavadushti).. AAM, 14 (Supplement 1), 370-383. doi:10.5455/AAM.59828



Turabian Style

S, Archana, and Laxmipriya Dei. 2025. A Randomized Controlled Trial of Palasadi Basti and Pathadi Choorna versus Metformin Hydrochloride in the Management of Polycystic Ovarian Syndrome (Artavadushti).. Annals of Ayurvedic Medicine, 14 (Supplement 1), 370-383. doi:10.5455/AAM.59828



Chicago Style

S, Archana, and Laxmipriya Dei. "A Randomized Controlled Trial of Palasadi Basti and Pathadi Choorna versus Metformin Hydrochloride in the Management of Polycystic Ovarian Syndrome (Artavadushti).." Annals of Ayurvedic Medicine 14 (2025), 370-383. doi:10.5455/AAM.59828



MLA (The Modern Language Association) Style

S, Archana, and Laxmipriya Dei. "A Randomized Controlled Trial of Palasadi Basti and Pathadi Choorna versus Metformin Hydrochloride in the Management of Polycystic Ovarian Syndrome (Artavadushti).." Annals of Ayurvedic Medicine 14.Supplement 1 (2025), 370-383. Print. doi:10.5455/AAM.59828



APA (American Psychological Association) Style

S, A. & Dei, . L. (2025) A Randomized Controlled Trial of Palasadi Basti and Pathadi Choorna versus Metformin Hydrochloride in the Management of Polycystic Ovarian Syndrome (Artavadushti).. Annals of Ayurvedic Medicine, 14 (Supplement 1), 370-383. doi:10.5455/AAM.59828