E-ISSN 2347-6923 | ISSN 2277-4092
 

Original Research 


An open- label, single- arm pilot study to evaluate the efficacy of Lashuna capsule in psychological symptoms during menopausal transition.

Kavyashree Kulamarva , Savitha HP.

Abstract
Menopause is a physiological process denoted as “Rajonivrutti” (Cessation of menstruation) in ayurveda. When it causes discomfort either to mind or body, attains a disease state requiring medical interference. Psychological variations are a major concern during menopausal transition. Approximately 80% of women suffer from psychological symptoms during this period. Lashuna (Garlic) helps to uphold psychological health through vata-kaphahara (pacifying vata-kapha humors), medhya (Nootropic) and rasayana (Rejuvenation) property as well as its action on neurotransmitters. 30 women between the age group 45 to 55 years undergoing menopausal transition were screened using Menopause rating scale. Selected women were administered with Lashuna capsule containing 500 mg of aqueous extract of garlic. Outcome was assessed after thirty days of treatment and 15 days of follow up. At the end of 30 days of intervention, subjects reported a significant reduction in psychological symptoms such as irritability, anxiety, depression, and sleep problem (P< 0.05).The results indicate that “vata kaphahara” (pacifying vata-kapha humors), nootropic (medhya), rejuvenating (rasayana) property along with clearing the bodily channels (srotoshodhana), garlic may help in reducing psychological complaints of Menopausal transition. Moreover nootropic, antidepressant, anxiolytic and adaptogenic activities of Allium sativum has been proven by several research. This permits larger clinical trials to validate the findings of this pilot study.

Key words: Anti-depressant; Anxiolytic; Lashuna capsule; Menopausal transition; Nootropic


 
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Pubmed Style

KK, HP S, . An open- label, single- arm pilot study to evaluate the efficacy of Lashuna capsule in psychological symptoms during menopausal transition.. AAM. 2023; 12(2): 169-177. doi:10.5455/AAM.110271


Web Style

KK, HP S, . An open- label, single- arm pilot study to evaluate the efficacy of Lashuna capsule in psychological symptoms during menopausal transition.. https://www.aamjournal.in/?mno=110271 [Access: December 05, 2023]. doi:10.5455/AAM.110271


AMA (American Medical Association) Style

KK, HP S, . An open- label, single- arm pilot study to evaluate the efficacy of Lashuna capsule in psychological symptoms during menopausal transition.. AAM. 2023; 12(2): 169-177. doi:10.5455/AAM.110271



Vancouver/ICMJE Style

KK, HP S, . An open- label, single- arm pilot study to evaluate the efficacy of Lashuna capsule in psychological symptoms during menopausal transition.. AAM. (2023), [cited December 05, 2023]; 12(2): 169-177. doi:10.5455/AAM.110271



Harvard Style

, K. K., HP, S. & (2023) An open- label, single- arm pilot study to evaluate the efficacy of Lashuna capsule in psychological symptoms during menopausal transition.. AAM, 12 (2), 169-177. doi:10.5455/AAM.110271



Turabian Style

, Kavyashree Kulamarva, Savitha HP, and . 2023. An open- label, single- arm pilot study to evaluate the efficacy of Lashuna capsule in psychological symptoms during menopausal transition.. Annals of Ayurvedic Medicine, 12 (2), 169-177. doi:10.5455/AAM.110271



Chicago Style

, Kavyashree Kulamarva, Savitha HP, and . "An open- label, single- arm pilot study to evaluate the efficacy of Lashuna capsule in psychological symptoms during menopausal transition.." Annals of Ayurvedic Medicine 12 (2023), 169-177. doi:10.5455/AAM.110271



MLA (The Modern Language Association) Style

, Kavyashree Kulamarva, Savitha HP, and . "An open- label, single- arm pilot study to evaluate the efficacy of Lashuna capsule in psychological symptoms during menopausal transition.." Annals of Ayurvedic Medicine 12.2 (2023), 169-177. Print. doi:10.5455/AAM.110271



APA (American Psychological Association) Style

, K. K., HP, S. & (2023) An open- label, single- arm pilot study to evaluate the efficacy of Lashuna capsule in psychological symptoms during menopausal transition.. Annals of Ayurvedic Medicine, 12 (2), 169-177. doi:10.5455/AAM.110271