Review Article 


Ayurveda interventions in the management of Duchenne Muscular Dystrophy – A Review

Vijay Kumar Pathak, Arun Kumar Mahapatra, Rajagopala S..

Abstract
Abstract
Duchenne Muscular Dystrophy (DMD) is a heterogeneous group of inherited disorders caused due to mutation in the gene for the protein dystrophin, located on the short arm of the X chromosome in the Xp21 region. It is characterized by proximal muscle weakness, calf hypertrophy, frequently developing contractures, and loss of walking by the 2nd decade. Patients are predisposed to severe, fatal pulmonary infections and lose their lives due to dysfunction of muscles involving the respiratory system. The incidence is 1 in 5000 live boys.
Objective: To review existing human case reports and clinical trials for treating Duchenne muscular dystrophy through the Panchakarma interventions.
Design: The literature research comprised an electronic database from January 2000 to April 2021. The study included MEDLINE, PubMed, The Cochrane Library, Google scholar, Ayush research portal and DHARA database. Search terms were used “Duchenne muscular dystrophy”, “Ayurveda”, “Panchakarma”, “DMD” No limits were used. The search strategy was adapted for each database as necessary. Only trials on humans were included in the patient review. The study applied inclusion criteria while screening the records.
Intervention: Treatment with any regimen of “Panchakarma”.
Outcome measures: Number and results of studies identified in the review.
Results: Seventeen articles were screened; Eight human trials met inclusion criteria. Ayurvedic Panchakarma based procedures effectively relieve the signs and symptoms and reduce the CPK level in children with DMD. There are only few studies published in Ayurveda in the management of DMD. The Conventional System of medicine and Ayurveda System of medicine are at the same level in the case of DMD for therapeutic purposes as there is no permanent cure for this disease in both systems. A combined approach should be made to manage this disease with the conventional method of medicine and Ayurveda. The integrative approach could open new hope for patients of DMD, and it is a need of time.

Key words: Duchenne Muscular Dystrophy, Dystrophin, Panchakarma, Ayurveda, Serum CPK


 
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How to Cite this Article
Pubmed Style

VKP, AKM, S. R. Ayurveda interventions in the management of Duchenne Muscular Dystrophy – A Review. AAM. 2022; 11(3): 243-255. doi:10.5455/AAM.119753


Web Style

VKP, AKM, S. R. Ayurveda interventions in the management of Duchenne Muscular Dystrophy – A Review. https://www.aamjournal.in/?mno=119753 [Access: November 22, 2022]. doi:10.5455/AAM.119753


AMA (American Medical Association) Style

VKP, AKM, S. R. Ayurveda interventions in the management of Duchenne Muscular Dystrophy – A Review. AAM. 2022; 11(3): 243-255. doi:10.5455/AAM.119753



Vancouver/ICMJE Style

VKP, AKM, S. R. Ayurveda interventions in the management of Duchenne Muscular Dystrophy – A Review. AAM. (2022), [cited November 22, 2022]; 11(3): 243-255. doi:10.5455/AAM.119753



Harvard Style

, V. K. P., , . A. K. M. & S., . R. (2022) Ayurveda interventions in the management of Duchenne Muscular Dystrophy – A Review. AAM, 11 (3), 243-255. doi:10.5455/AAM.119753



Turabian Style

, Vijay Kumar Pathak, Arun Kumar Mahapatra, and Rajagopala S.. 2022. Ayurveda interventions in the management of Duchenne Muscular Dystrophy – A Review. Annals of Ayurvedic Medicine, 11 (3), 243-255. doi:10.5455/AAM.119753



Chicago Style

, Vijay Kumar Pathak, Arun Kumar Mahapatra, and Rajagopala S.. "Ayurveda interventions in the management of Duchenne Muscular Dystrophy – A Review." Annals of Ayurvedic Medicine 11 (2022), 243-255. doi:10.5455/AAM.119753



MLA (The Modern Language Association) Style

, Vijay Kumar Pathak, Arun Kumar Mahapatra, and Rajagopala S.. "Ayurveda interventions in the management of Duchenne Muscular Dystrophy – A Review." Annals of Ayurvedic Medicine 11.3 (2022), 243-255. Print. doi:10.5455/AAM.119753



APA (American Psychological Association) Style

, V. K. P., , . A. K. M. & S., . R. (2022) Ayurveda interventions in the management of Duchenne Muscular Dystrophy – A Review. Annals of Ayurvedic Medicine, 11 (3), 243-255. doi:10.5455/AAM.119753




Current Issue : 2022, Vol: 11, Issue: 3
E-ISSN : 2347-6923
ISSN : 2277-4092
ISSUES : 4 per year
PUBLISHER : Association of Ayurvedic Physicians of India

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