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Effect of Majoon-e-Falasafa and Safoof-e-Aqarqarha in Hypothyroidism - A Randomized Controlled Clinical study

Kaleem Ahmad, Mansoor Ahmad Siddiqui, Mohd Aleemuddin Quamri.

Abstract
Objective: Hypothyroidism is one of the most common endocrinal disorders worldwide characterize as a clinical syndrome that occurs due to decreased functioning of thyroid hormones lead to varieties of clinical and biochemical signs and symptoms. Autoimmunity, 131I-therapy, and thyroidectomy account for 90% of the causes of thyroid hormone deficiency. The use of levothyroxine is lifelong and controversial in certain conditions. Today, there is a need to seek herbs as an alternative therapy. The present clinical trial was conducted to evaluate the effect of Majoon-e-Falasafa and Safoof-e-Aqarqarha in Hypothyroidism - A Randomized Controlled Clinical Study. Methods: This study was carried out on 40 patients after the screening of 56 subjects. All enrolled patients were randomized by computer-generated random numbers into two groups, 30 in the test group and 10 in the control group, and assessing on subjective & objective parameters. All data analyses were done by using paired proportion tests and student t-test before and after to assess the effect of interventions. Result: The demographic data of both groups were similar at baseline. The all-subjective & objective parameters significantly improved (P<0.001) in both groups except weight change, loss of hair, free T3, and T4 (P>0.05). The TSH was significantly improved by 26.7% (P=0.013) in the test group and 50% (P=0.06) in the control group at baseline and after treatment. No significant difference (intergroup P>0.05) were observed in all subjective and objective parameters between groups at baseline and after treatment except free T4. Conclusion: The test intervention has an effect on subjective and objective parameters but the control group was superior to the test group. [Trial registration: CTRI/2018/02/011768].

Key words: Hypothyroidism, Majoon-e-Falasafa, Aqarqraha (Anacyclus pyrethrum), levothyroxine, Herbal, Autoimmunity


 
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Pubmed Style

Ahmad K, MAS, Quamri MA. Effect of Majoon-e-Falasafa and Safoof-e-Aqarqarha in Hypothyroidism - A Randomized Controlled Clinical study. AAM. 2022; 11(1): 10-21. doi:10.5455/AAM.2893


Web Style

Ahmad K, MAS, Quamri MA. Effect of Majoon-e-Falasafa and Safoof-e-Aqarqarha in Hypothyroidism - A Randomized Controlled Clinical study. https://www.aamjournal.in/?mno=2893 [Access: May 06, 2022]. doi:10.5455/AAM.2893


AMA (American Medical Association) Style

Ahmad K, MAS, Quamri MA. Effect of Majoon-e-Falasafa and Safoof-e-Aqarqarha in Hypothyroidism - A Randomized Controlled Clinical study. AAM. 2022; 11(1): 10-21. doi:10.5455/AAM.2893



Vancouver/ICMJE Style

Ahmad K, MAS, Quamri MA. Effect of Majoon-e-Falasafa and Safoof-e-Aqarqarha in Hypothyroidism - A Randomized Controlled Clinical study. AAM. (2022), [cited May 06, 2022]; 11(1): 10-21. doi:10.5455/AAM.2893



Harvard Style

Ahmad, K., , . M. A. S. & Quamri, . M. A. (2022) Effect of Majoon-e-Falasafa and Safoof-e-Aqarqarha in Hypothyroidism - A Randomized Controlled Clinical study. AAM, 11 (1), 10-21. doi:10.5455/AAM.2893



Turabian Style

Ahmad, Kaleem, Mansoor Ahmad Siddiqui, and Mohd Aleemuddin Quamri. 2022. Effect of Majoon-e-Falasafa and Safoof-e-Aqarqarha in Hypothyroidism - A Randomized Controlled Clinical study. Annals of Ayurvedic Medicine, 11 (1), 10-21. doi:10.5455/AAM.2893



Chicago Style

Ahmad, Kaleem, Mansoor Ahmad Siddiqui, and Mohd Aleemuddin Quamri. "Effect of Majoon-e-Falasafa and Safoof-e-Aqarqarha in Hypothyroidism - A Randomized Controlled Clinical study." Annals of Ayurvedic Medicine 11 (2022), 10-21. doi:10.5455/AAM.2893



MLA (The Modern Language Association) Style

Ahmad, Kaleem, Mansoor Ahmad Siddiqui, and Mohd Aleemuddin Quamri. "Effect of Majoon-e-Falasafa and Safoof-e-Aqarqarha in Hypothyroidism - A Randomized Controlled Clinical study." Annals of Ayurvedic Medicine 11.1 (2022), 10-21. Print. doi:10.5455/AAM.2893



APA (American Psychological Association) Style

Ahmad, K., , . M. A. S. & Quamri, . M. A. (2022) Effect of Majoon-e-Falasafa and Safoof-e-Aqarqarha in Hypothyroidism - A Randomized Controlled Clinical study. Annals of Ayurvedic Medicine, 11 (1), 10-21. doi:10.5455/AAM.2893








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