Cytotoxic Potential of Bhallataka Rasayana 
in MCF-7 & HT-29 Cancer cell lines

Shivani Sharma; Pramod R Yadav; Galib R; Pradeep Kumar Prajapati

doi:10.5455/AAM.59654

2026, Vol: 15, Issue: 1

15 / 1Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Original Article

AAM. 2026; 15(Supplement 1): 153-161

doi: 10.5455/AAM.59654

Cytotoxic Potential of Bhallataka Rasayana in MCF-7 & HT-29 Cancer cell lines

Shivani Sharma, Pramod R Yadav, Galib R, Pradeep Kumar Prajapati.

Abstract
Cancer, the second most prevalent non-communicable disease after ischemic heart disease, presents significant challenges to medical science due to its severe impact on health. Ayurveda, an ancient system of medicine, offers a diverse range of potent cancer treatments that can be integrated into conventional oncological therapies. One such Ayurvedic formulation is Bhallataka Rasayana, derived from Semecarpus anacardium Linn. f., which is referenced in traditional Ayurvedic literature for its therapeutic benefits. This study investigates the cytotoxic potential of Bhallataka Rasayana on breast (MCF7) and colon (HT29) cancer cell lines. The in vitro cytotoxic activity of Bhallataka Rasayana was evaluated using the MTT assay across different concentrations to determine the half-maximal inhibitory concentration (IC50). The results demonstrated that the extract of Bhallataka Rasayana exhibited significant cytotoxic effects against MCF7 and HT-29 cell lines, with IC50 values of 1.0 µg/mL and 2.0 µg/mL, respectively. These findings are notable when compared to the IC50 values of Doxorubicin, a standard chemotherapeutic agent, which are 0.5 µg/mL for MCF7 and 0.3 µg/mL for HT-29. The study highlights the potential of Bhallataka Rasayana as a complementary therapeutic agent in cancer treatment.

Key words: [Semecarpus] [Breast cancer] [MCF-7 Cells] [Anti-oxidant] [Doxorubucin]

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by Shivani Sharma Articles by Pramod R Yadav Articles by Galib R Articles by Pradeep Kumar Prajapati
	on Google
	on Google Scholar

How to Cite this Article

Pubmed Style

Sharma S, Yadav PR, R G, Prajapati PK. Cytotoxic Potential of Bhallataka Rasayana in MCF-7 & HT-29 Cancer cell lines. AAM. 2026; 15(Supplement 1): 153-161. doi:10.5455/AAM.59654

Web Style

Sharma S, Yadav PR, R G, Prajapati PK. Cytotoxic Potential of Bhallataka Rasayana in MCF-7 & HT-29 Cancer cell lines. https://www.aamjournal.in/?mno=59654 [Access: February 24, 2026]. doi:10.5455/AAM.59654

AMA (American Medical Association) Style

Sharma S, Yadav PR, R G, Prajapati PK. Cytotoxic Potential of Bhallataka Rasayana in MCF-7 & HT-29 Cancer cell lines. AAM. 2026; 15(Supplement 1): 153-161. doi:10.5455/AAM.59654

Vancouver/ICMJE Style

Sharma S, Yadav PR, R G, Prajapati PK. Cytotoxic Potential of Bhallataka Rasayana in MCF-7 & HT-29 Cancer cell lines. AAM. (2026), [cited February 24, 2026]; 15(Supplement 1): 153-161. doi:10.5455/AAM.59654

Harvard Style

Sharma, S., Yadav, . P. R., R, . G. & Prajapati, . P. K. (2026) Cytotoxic Potential of Bhallataka Rasayana in MCF-7 & HT-29 Cancer cell lines. AAM, 15 (Supplement 1), 153-161. doi:10.5455/AAM.59654

Turabian Style

Sharma, Shivani, Pramod R Yadav, Galib R, and Pradeep Kumar Prajapati. 2026. Cytotoxic Potential of Bhallataka Rasayana in MCF-7 & HT-29 Cancer cell lines. Annals of Ayurvedic Medicine, 15 (Supplement 1), 153-161. doi:10.5455/AAM.59654

Chicago Style

Sharma, Shivani, Pramod R Yadav, Galib R, and Pradeep Kumar Prajapati. "Cytotoxic Potential of Bhallataka Rasayana in MCF-7 & HT-29 Cancer cell lines." Annals of Ayurvedic Medicine 15 (2026), 153-161. doi:10.5455/AAM.59654

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Sharma, S., Yadav, . P. R., R, . G. & Prajapati, . P. K. (2026) Cytotoxic Potential of Bhallataka Rasayana in MCF-7 & HT-29 Cancer cell lines. Annals of Ayurvedic Medicine, 15 (Supplement 1), 153-161. doi:10.5455/AAM.59654

About Annals of Ayurvedic Medicine

Contact Information

How to cite this article


About Annals of Ayurvedic Medicine Annals of Ayurvedic Medicine (AAM) is the organ of ‘Association of Ayurvedic Physicians of India\'(AAPI), which is a national representative body of Ayu ... Read more. For best results, please use Internet Explorer or Google Chrome.	Contact Information Editorial Office : Prof Sanjeev Rastogi Vatsala Hospital, Tulsi Das Marg, Lucknow-226003, INDIA Main Office : 6, Ganga Bag Colony, Lanka, Varanasi -221005, INDIA Editorial Contact: Email: info@sapi.org.in Email: rastogisanjeev@rediffmail.com Mobile: 0091-9415022955