E-ISSN 2347-6923 | ISSN 2277-4092
 
2025, Vol: 14, Issue: 2
14 / 2Current Issue Online FirstArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

Cover letter

Original Research
Online Published: 02 Nov 2013
 
AAM. 2013; 2(3): 61-71


Antioxidant role of fruit extract of Emblica officanialis (amla) against arsenic induced renal-toxicity in mice.

Manish Kumar Singh, Devendra Kumar Katiyar, Suraj Singh Yadav, Vineeta Gupta, Sanjay Khattri.


Abstract
The sub-chronic exposure of arsenic is associated with human health risk including renal-toxicity, hepatic-toxicity and neuro-toxicity. The protective efficacy of fruit extract of Emblica-officinalis (amla) was studied in Balb/c mice against arsenic induced renal toxicity.
The study was divided in four groups having five mice in each group. Increased arsenic level in renal tissue associated with enhanced oxidative stress, decrease in the levels of glutathione and activity of superoxide dismutase, catalase and glutathione peroxidase was observed in mice exposed to arsenic (sodium arsenite, 3 mg/kg body weight, p.o., 30 days).
Simultaneous treatment of amla (500 mg/kg body weight, p.o., 30 days) and arsenic exposed mice caused an increase antioxidant enzyme and decreases arsenic levels in renal tissue as compared to arsenic treated mice. No significant effect on any of these parameters was observed in mice treated with amla (500 mg/kg body weight, p.o., 30 days) alone compared to controls. A significant protective efficacy in mice simultaneously treated with arsenic and amla suggested the renal protective efficacy of amla.

Key words: Arsenic, oxidative stress, amla, mice


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Manish Kumar Singh
Articles by Devendra Kumar Katiyar
Articles by Suraj Singh Yadav
Articles by Vineeta Gupta
Articles by Sanjay Khattri
on Google
on Google Scholar

How to Cite this Article
Pubmed Style

Manish Kumar Singh, Devendra Kumar Katiyar, Suraj Singh Yadav, Vineeta Gupta, Sanjay Khattri. Antioxidant role of fruit extract of Emblica officanialis (amla) against arsenic induced renal-toxicity in mice. . AAM. 2013; 2(3): 61-71.

Web Style

Manish Kumar Singh, Devendra Kumar Katiyar, Suraj Singh Yadav, Vineeta Gupta, Sanjay Khattri. Antioxidant role of fruit extract of Emblica officanialis (amla) against arsenic induced renal-toxicity in mice. . https://www.aamjournal.in/?mno=36151 [Access: September 13, 2024].

AMA (American Medical Association) Style

Manish Kumar Singh, Devendra Kumar Katiyar, Suraj Singh Yadav, Vineeta Gupta, Sanjay Khattri. Antioxidant role of fruit extract of Emblica officanialis (amla) against arsenic induced renal-toxicity in mice. . AAM. 2013; 2(3): 61-71.


Vancouver/ICMJE Style

Manish Kumar Singh, Devendra Kumar Katiyar, Suraj Singh Yadav, Vineeta Gupta, Sanjay Khattri. Antioxidant role of fruit extract of Emblica officanialis (amla) against arsenic induced renal-toxicity in mice. . AAM. (2013), [cited September 13, 2024]; 2(3): 61-71.


Harvard Style

Manish Kumar Singh, Devendra Kumar Katiyar, Suraj Singh Yadav, Vineeta Gupta, Sanjay Khattri (2013) Antioxidant role of fruit extract of Emblica officanialis (amla) against arsenic induced renal-toxicity in mice. . AAM, 2 (3), 61-71.


Turabian Style

Manish Kumar Singh, Devendra Kumar Katiyar, Suraj Singh Yadav, Vineeta Gupta, Sanjay Khattri. 2013. Antioxidant role of fruit extract of Emblica officanialis (amla) against arsenic induced renal-toxicity in mice. . Annals of Ayurvedic Medicine, 2 (3), 61-71.


Chicago Style

Manish Kumar Singh, Devendra Kumar Katiyar, Suraj Singh Yadav, Vineeta Gupta, Sanjay Khattri. "Antioxidant role of fruit extract of Emblica officanialis (amla) against arsenic induced renal-toxicity in mice. ." Annals of Ayurvedic Medicine 2 (2013), 61-71.


MLA (The Modern Language Association) Style

Manish Kumar Singh, Devendra Kumar Katiyar, Suraj Singh Yadav, Vineeta Gupta, Sanjay Khattri. "Antioxidant role of fruit extract of Emblica officanialis (amla) against arsenic induced renal-toxicity in mice. ." Annals of Ayurvedic Medicine 2.3 (2013), 61-71. Print.


APA (American Psychological Association) Style

Manish Kumar Singh, Devendra Kumar Katiyar, Suraj Singh Yadav, Vineeta Gupta, Sanjay Khattri (2013) Antioxidant role of fruit extract of Emblica officanialis (amla) against arsenic induced renal-toxicity in mice. . Annals of Ayurvedic Medicine, 2 (3), 61-71.


Author LoginReviewer LoginAbout PublisherEditorial PoliciesEditorial Review PolicyPeer Review PolicyEditorial & Peer Review ProcessAuthor's Rights and ObligationsPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyProtection of Research Participants (Statement On Human And Animal Rights)Privacy PolicyCorrections, Retractions & Expressions of ConcernSelf-Archiving PoliciesDigital Archiving & Preservation PoliciesStatement of Informed ConsentAdvertising PolicyLicense InformationCopyright Information

About Annals of Ayurvedic Medicine

Annals of Ayurvedic Medicine (AAM) is the organ of ‘Association of Ayurvedic Physicians of India'(AAPI), which is a national representative body of Ayur ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information


Editorial Office :

Prof Sanjeev Rastogi

Vatsala Hospital, Tulsi Das Marg, Lucknow-226003, INDIA

Main Office :

6, Ganga Bag Colony, Lanka, Varanasi -221005, INDIA

Editorial Contact:

Email: rastogisanjeev@rediffmail.com

Mobile: 0091-9415022955